Ioan Gruffudd
Reed Richards / Mr. Fantastic
Jessica Alba
Sue Richards / Invisible Woman
Chris Evans
Johnny Storm / Human Torch
Michael Chiklis
Ben Grimm / The Thing
Julian McMahon
Victor von Doom / Doctor Doom
Laurence Fishburne
Norrin Radd / Silver Surfer (voice)
Doug Jones
Norrin Radd / Silver Surfer
Kerry Washington
Alicia Masters
Andre Braugher
General Hager
Beau Garrett
Frankie Raye
Brian Posehn
Priest
Zach Grenier
James Sherman / Rafke
Kenneth Welsh
Dr. Jeff Wagner
Kevin McNulty
Baxter Building Doorman
Andy Stahl
Tailor
Debbie Timuss
Hot Party Girl #1
Moneca Delain
Hot Party Girl #2
Yan-Kay Crystal Lowe
Hot Party Girl #3
Vanessa Lachey
Johnny's Wedding Date
Stan Lee
Stan Lee - Rejected Wedding Guest
Gonzalo Menendez
Lieutenant
Giuliana Rancic
Entertainment Reporter
Lauren Sánchez Bezos
Fox News Reporter
Benjamin Ayres
Guard #1
Patricia Harras
Fan Four Receptionist
Fareed Abdelhak
Egyptian Tour Guide
Dawn Chubai
Anchorwoman
Alicia Thorgrimsson
New York Pedestrian
Valerie Tian
New York Teen Girl #1
Jeanna Haddow
New York Teen Girl #2
Ali Costigan
New York Teen Girl #3
Suzanne Ristic
Airline Woman
Michasha Armstrong
Wedding Security
Ulla Friis
Danish News Anchor (uncredited)
Nimet Kanji
Tourist in Egypt (uncredited)